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Interview

American Humane Society amplifying its mission with AI | Box AI-First Podcast EP 11

  • December 8, 2025
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In this episode of the AI First Podcast, Box Chief Customer Officer ​@Jon, speaks with Karthik Devarajan, Chief Technology Officer at American Humane Society, the nation's first humane organization dedicated to protecting animals for over 150 years.

Karthik discusses how AI is transforming operations across American Humane Society's diverse programs, from disaster rescue to service dog training, enhancing their mission to protect animals at scale. American Humane Society is using AI to modernize how it manages vast amounts of data across its programs, leveraging technology to identify patterns and assist with critical decision-making.

 

Karthik shares insights into how AI is improving efficiency, including AI-assisted audits, image analysis from rescue operations, and reducing manual processes to save time for staff so they can focus on what truly matters - animal welfare. Whether you're in the nonprofit space, technology, or operations leadership, you'll find valuable lessons in how to responsibly implement AI to amplify your mission.

 

(00:00) Introduction to American Humane Society’s 150-year mission

(02:04) Karthik’s role and scope of responsibility at American Humane Society

(05:23) Using AI to amplify animal welfare efforts through data analysis

(08:10) Innovation in a legacy organization

(10:00) AI’s impact on efficiency

(12:29) Applying AI to farm certification and rescue operations

(15:52) Building internal AI champions and fostering a culture of innovation

(18:47) Overcoming skepticism and demonstrating AI’s value through small wins

(20:29) Measuring AI’s impact on time savings and decision-making

(23:10) Using AI for enhanced audits and operational insights

(26:18) Rethinking data management and supporting AI adoption through collaboration

(30:43) How AI aligns with American Humane Society’s core values of compassion and trust

(34:02) Lessons learned from early AI pilots

(37:52) Scaling AI adoption and using technology to amplify kindness

(42:32) Advice for other nonprofits looking to integrate AI into their operations

(45:12) Managing AI risks through transparency and policy

(48:30) How to maintain trust with staff and stakeholders when adopting AI

(51:01) Key takeaways on balancing innovation with mission

(53:10) The importance of continual learning and iteration in AI adoption

(55:25) Preparing for future AI-driven initiatives in animal welfare

(58:10) Final thoughts on staying mission-driven while embracing AI technology

(59:50) Closing remarks and gratitude for AI’s role in advancing American Humane Society’s mission

 

 

Question for our Community:

How are you managing AI deployment in your organization?